Muscular dystrophy treatment in India
NeuroGen Brain & Spine Institute commenced on 17th December 2008. From treating around 150 patients in the initial year we have steadily reached a point to where we treat approximately 250 patients in a month. We have not only expanded from a small facility to an 11 storey building, in a beautiful, homely, locality, but also grown in terms of manpower and resources. We began as a team of 6 professionals in the year 2008 but have now expanded to a larger family consisting of almost 200 inhouse and outsourced employees. The entire set up of the hospital has been designed to be patient centric.
In the past donated organs were transplanted to replace the diseased or failed organs in the recipients. Soon the number of recipients exceeded the number of donated. To overcome this demand, cell therapy offered the possibility of replacement of the damaged cells of tissue with new cells. Stem cell infusion helps to treat a plethora of conditions including cerebral palsy, spinal cord injury, intellectual disability, and other neurodegenerative syndromes as well.
Stem cells have the potential to develop into different cells of the tissues (of the body) and the ability of self-renewal. When serving as a repair system, the stem cells divide without limit as long as the person is alive. As they divide, they remain as stem cells or develop into cells with more specialized functions, like a brain cell or a muscle cell.
Stem cells, from different sources, have three common properties: The stem cells do not have tissue-specific structures to perform specialized functions.
Impairments linked to neuromuscular conditions are usually irreversible due to inadequate cell regeneration or impaired cells in the central nervous system. It was observed that the cellular characteristics of autologous stem cells had the capability of treating major neurological disorders without incurring any side effects. With their neurotrophic properties, self-renewal & differentiation capacity, and immune modulation effects, the bone marrow-derived stem cells are considered as a promising candidate for treating disorders related to the nervous system.
For cell treatment, bone marrow derived mesenchymal stem cells are isolated from the marrow tissue (extracted from the patient’s hip bone) in an expedited, painless and safe way. By centrifugation procedure, a sufficient number of stem cells are separated from the unwanted tissue within a few hours. These injectable stem cells are infused intrathecally into the spinal area or the damaged muscle points, as per the need of the patients.
These bone marrow-derived stem cells have many useful properties that lead to great clinical improvement in post-cell-based therapy. According to various clinical trials, treatment with bone marrow derived mesenchymal stem cells have shown improvement in patients with traumatic brain injury, spinal cord injury and other neurological disorders through axonal sprouting and remyelination, potential to replace/protect the damaged neurons/cells, and neovascularization.
How do the infused stem cells act? Once infused into the body,
– The infused stem cells journey toward the nervous system and blend into the neural circuits to mend or improve the disrupted synaptic transmission.
– Post infusion, improved neuropathological condition, upregulated Aß clearance and reduced deposition is detected within a short period.
– The infused stem cells reduce neuroinflammation and provide protective immunomodulatory effect.
– The stem cells secrete neurotrophic influence and nerve growth factors, bringing cognitive and memory improvement in patients.
Apart from encouraging effects, renewed brain plasticity is also observed in patients following intrathecal delivery of stem cells. With the new medical breakthrough in stem cell therapy, the treatment has become a highly sought-after curative. To know about the treatment efficacy, one must understand the efficiency of stem cells in terms of engraftment, migration, cytokines and growth factors. However, cell-based therapy is a promising contribution to regenerative medicine and has gained considerable clinical attention. Read extra details on NeuroGen BSI.
Many specialists recommend starting physical therapy as early as possible to prevent future complications like contractures-a shortening of muscles and tendons that can be painful and is common in spastic cerebral palsy. Strength training exercises are also helpful for children with dyskinetic cerebral palsy who have loose muscles and may experience atrophy. Occupational therapy helps children with cerebral palsy improve fine motor skills. In general, physical therapy is used to improve gross motor function, but it doesn’t focus on fine motor function. People with cerebral palsy struggle with coordinating these skills for tasks such as grasping a spoon and bringing it to their mouth. But occupational therapists often work with physical and speech therapists to build a complete therapy plan.
A few tips to help your child with autism: ADS support groups – Joining an ASD support group is a great way to meet other families dealing with the same challenges you are. Parents can share information, get advice, and lean on each other for emotional support. Just being around others in the same boat and sharing their experience can go a long way toward reducing the isolation many parents feel after receiving a child’s diagnosis. Respite care – Every parent needs a break now and again. And for parents coping with the added stress of ASD, this is especially true. In respite care, another caregiver takes over temporarily, giving you a break for a few hours, days, or even weeks. Individual, marital, or family counseling – If stress, anxiety, or depression is getting to you, you may want to see a therapist of your own. Therapy is a safe place where you can talk honestly about everything you’re feeling-the good, the bad, and the ugly. Marriage or family therapy can also help you work out problems that the challenges of life with an autistic child are causing in your spousal relationship or with other family members.
What’s the long-term outlook? Some people lead full and productive lives after a spinal cord injury. However, there are severe potential effects of a spinal cord injury. The vast majority of people will need assistive devices such as walkers or wheelchairs to deal with loss of mobility, and some may even be paralyzed from the neck down. You may need assistance with daily living activities and learn to perform tasks differently. Pressure sores and urinary tract infections are common complications. You also may expect to undergo intense rehabilitation treatment for your spinal cord injury.
Did you know that stem cells, unlike other cells in the body, continue to divide for long periods of time and can help strengthen the immune system, effectively fighting infections and pathogens from the external environment. In addition, stem cells in the placenta and umbilical cord are important sources of platelets and red cells, which carry oxygen and nutrients to the blood. Stem cell harvesting can be done regardless of the time of birth: vaginal birth, caesarean section, multiple birth, premature birth or water birth.
Persistent challenges ranging from severe to mild deficit in social communication and interaction, across a number of contexts, are the characteristics of Autism Spectrum Disorder, accompanied with the need for sameness, or a routine, which triggers an exaggerated response, when tampered with. Let’s begin with the earliest signs of Autism, which could be presented by a lack of responsiveness, or a lack of eye contact. Children with Autism in the early stages may not show any response to name, or look directly at the person when spoken to. In some cases of Autism, symptoms may present as a regression of social and cognitive milestones between the age of 2- 4 years, where the child’s development seems to be on track, however, he/she starts to slowly ‘lose’ the milestones. Commonly, the following signs and symptoms of autism spectrum disorders are observed. Read more info Autism Treatment.